LinksMedicus.com - Internal Medicine Articles
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About LinksMedicus.com - Internal Medicine Articles
Welcome to the official Internal Medicine channel by LinksMedicus.com on WhatsApp! Our goal is to share impactful articles with healthcare professionals. Each morning, you’ll receive a brief summary of a noteworthy study, along with: • A link to a more detailed summary on LinksMedicus.com • The link to the original article. Stay informed with the latest research, clinical updates, and innovations in Internal Medicine!
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Posts
*Internal Medicine Article of the Day!* Just released in @NatureMedicine: *Large Cohort Study on GLP-1 Receptor Agonists* 🩺📊 Why it matters: *A real-world look at benefits vs. risks in T2DM*. 🔑 Key Findings: ✅ *Cardiac arrest ↓22%* (HR 0.78), *HF ↓11%* (HR 0.89) 🧠 Neuro benefits: *Alzheimer’s ↓12%, suicidal ideation ↓10%* 💔 *Coagulopathy and clotting disorders ↓8%, acute kidney injury ↓12%* ⚠️ Risks: *Drug-induced pancreatitis ↑146% 😮, nephrolithiasis ↑15%, arthritis ↑11%* 📊 Study Design: - n=215,970 GLP-1RA users vs. 1.9M controls - 3.68 yrs median follow-up, propensity-score weighted ⚠️ Caveats: - Mostly older male (VA data) - *Observational design → residual confounding* 🔗 Full article: https://www.nature.com/articles/s41591-024-03412-w 🔗 Summary on LM: https://www.linksmedicus.com/news/observational-cohort-study-glp-1-receptor-agonists-demonstrate-wide-ranging-benefits-but-elevate-gastrointestinal-renal-and-musculoskeletal-risks/
*Internal Medicine Article of the Day!* Just released in JAC-Antimicrobial Resistance: *Short-Course Antibiotic Review* 🦠💊 *Why it matters:* Practical stewardship tips to fight resistance & reduce side effects *Key Strategies:* ✅ *Community-acquired pneumonia:* 5 days for mild/moderate outpatient cases, 7-10 days for severe/complicated. ✅ *Acute Bacterial Sinusitis:* 5-7 days for adults, 10-14 if pediatric (IDSA). ✅ *Uncomplicated Cystitis:* 5 days of nitrofurantoin or 3 days of TMP/SMX. ✅ *Skin/Soft Tissue Infections:* 5-6 days if uncomplicated, longer if complicated. ✅ *Intra-abdominal Infections:* 4 days with adequate source control. ✅ *GAS Pharyngitis:* 10 days of penicillin/amoxicillin remains standard to ensure bacterial eradication & ↓ rheumatic fever risk. ✅ *Perioperative prophylaxis:* <24h in most surgeries. ⚠️ *Caveats:* - Limited data for severe infections and immunocompromised patients. - Tailor treatment to individual patient factors and local resistance patterns. 🔗 *Full article:* https://academic.oup.com/jacamr/article/7/1/dlae215/7986017 🔗 *Summary on LM:* https://bit.ly/42DpqdV 🔗 For more articles, follow our *WhatsApp channel*: https://bit.ly/4jEzLwa