Atul’s Ophthalmology Pearls & OMO ( One Minute Ophthalmology)

Atul’s Ophthalmology Pearls & OMO ( One Minute Ophthalmology)

2/10/2025, 11:21:41 AM

# VISUAL II 👉🏼WHAT IS IT ? efficacy and safety in preventing flare-up in pharmacologically controlled noninfectious uveitis (10–35 mg prednisone and/or 1 IMT) 👉🏼 CONCLUSION The ADA group was less likely than the placebo group to have treatment failure the incidence of adverse and serious adverse events was similar between treatment groups.

Atul’s Ophthalmology Pearls & OMO ( One Minute Ophthalmology)

2/11/2025, 2:09:33 AM

# VISUAL III 👉🏼WHAT IS IT ? Long-term efficacy and safety of ADA in active or controlled noninfectious uveitis 👉🏼CONCLUSION * 60% of patients with active uveitis achieved quiescence at week 78, 66% of whom were corticosteroid free. * 74% of patients with inactive uveitis achieved quiescence at week 78, 93% of whom were corticosteroid free. * adverse events and serious adverse events were comparable to those in previous studies

Atul’s Ophthalmology Pearls & OMO ( One Minute Ophthalmology)

2/5/2025, 5:03:25 AM

# Paradoxical acute angle closure following use of pilocarpine ? 👉🏼 - spherophakia - zonular weakness from exfoliation syndrome - phacomorphic glaucoma,

Atul’s Ophthalmology Pearls & OMO ( One Minute Ophthalmology)

2/9/2025, 5:47:41 PM

# Visual I Study 👉🏼WHAT IS IT ? Adalimumab for noninfectious intermediate, posterior, or panuveitis 👉🏼 CONCLUSION * the ADA group was less likely than the placebo group to have treatment failure adverse events * serious adverse events were more common in the ADA group

Atul’s Ophthalmology Pearls & OMO ( One Minute Ophthalmology)

2/6/2025, 5:20:40 AM

# HURON study Chronic Uveitis evaluation of the Intravitreal Dexamethasone Implant * Study Questions : efficacy and safety of the injectable dexamethasone intravitreal implant at 2 doses (0.35 mg and 0.70 mg) compared to placebo (sham) * primary endpoint: vitreous haze grade 0 * Ozurdex group more likely than the sham group to have vitreous haze grade of 0 at 8 weeks * <5% of eyes developed IOp ≥35 mm hg and <10% had IOp ≥25 mm hg. * Cataracts developed in 15%

Atul’s Ophthalmology Pearls & OMO ( One Minute Ophthalmology)

2/4/2025, 8:57:46 AM

# Unilateral uveitis, open angle , raised IOP ? 💡Think of viral Toxoplasmosis

Atul’s Ophthalmology Pearls & OMO ( One Minute Ophthalmology)

2/1/2025, 8:05:51 AM

# What is NERVE HEAD SIGN of sickling ? 👉🏼 small vessels on the surface of the optic nerve head can exhibit intravascular occlusions, manifested as dark red spots

Atul’s Ophthalmology Pearls & OMO ( One Minute Ophthalmology)

1/31/2025, 5:55:57 AM

#What is COMMA sign in sickle cell disease? 👉🏼 Numerous comma-shaped thrombi dilate and occlude capillaries, most often in the inferior bulbar conjunctiva and fornix .

Atul’s Ophthalmology Pearls & OMO ( One Minute Ophthalmology)

2/3/2025, 5:53:13 AM

# Which drug can cause scleritis? 👆🏽Biphosponates

Atul’s Ophthalmology Pearls & OMO ( One Minute Ophthalmology)

2/7/2025, 10:40:42 AM

# SYCAMORE Study 👉🏼WHAT IS Adalimumab plus Methotrexate for JIA Uveitis 👉🏼CONCLUSION * ADA group was less likely than the placebo group to have treatment failure * a significantly greater proportion of patients in the adalimumab group than in the placebo group could eliminate or reduce topical corticosteroids. * the rate & number of adverse events per patient- year was higher in the ADA group than in the placebo group