Sarcoma is a type of cancer that primarily targets soft tissues, and it can be particularly aggressive and alarming. There are five main types, or histologies, of sarcoma that are most commonly linked to lymph node involvement. To make it easier to remember these, think of the acronym SCARE: Synovial Clear cell Angiosarcoma Rhabdomyosarcoma Epithelioid Each of these subtypes can present differently and may require unique approaches for diagnosis and treatment, highlighting the importance of early detection and careful management.