Medicine recalls 7 Feb Evening (Plz do check the key) 1. Patient with AIDs presented with respiratory symptoms. Drug given what does the drug inhibits A. Protein synthesis B. Cell wall synthesis C. *DNA synthesis* D. RNA synthesis E. 2. Tetanus scenario. Toxin is (no exo in options) A. Endo B. *Neuro* C. Entero D. E. 3. Which vaccine is conjugated with protein.... A. *Meningiococcal* B. Tetanus toxoid C. Pertussis D. Polio E. 4. Pertussis scenario.. Dx given. Drug to be given A. Ciprofloxacin B. *Erythromycin* C. Doxy D. E. 5. *Spina bifida occulta* repeat. Man with backache presented and doctor observed a tuft of hair 6. Which vitamin other than folate is thought to be responsible for NTDs. A. *Vitamin B12* B. Vit A Def C. Vit A excess D. Vit D Def E. Vit D excess 7. Heart ka aik tha with post valvular stenosis. Which cells/layer involved A. Collagen B. Elastic ? C. D. E. 8. Old age Patient presented with thigh trauma during operation continuous bleeding. Baseline coagulation profile deranged. PT , APTT raised fibrinogen and platelet count low. On inquiry, History of bruises since 06 months, no other abnormality. A. Sepsis and DIC ? (Investigations) B. Accidental heparin during surgery C. Warfarin used before surgery D. Occult carcinoma likely Prostate ? (Previous history) E. 9. Obese patient with myxedema. Thenar wasting and loss of sensation on lateral palmar aspect. A. Cubital tunnel syndrome B. Ulnar nerve C. *Carpel tunnel syndrome* D. E. 10. VEGF k action Ka poocha tha 11. Cholecystitis pain in upper abdomen. Dermatomes A. T5-7 B. *T7-9* C. D. E. 12. Data of age of 10 head of families was given. Calculate the mean Ans. *40.5* 13. Regarding Fat embolism syndrome what is true A. Can occur before 12 hours B. Fatal in over 80% of cases C. D. E. 14. Patient with vague symptoms of Cushing. The doctor thought that problem is at the level of receptor. Where is the receptor of cortisol located. A. Plasma membrane B. Nucleus C. DNA D. *Cytoplasm* E. 15. Child agitated, with coarse features, edema, ascites ... What is the underlying cause A. *Deficiency of protein in diet leading to hypoproteinemia* B. Deficiency of Calories in diet leading to hypoalbuminemia C. D. E. 16. A 20 years old patient presented with cough and dyspnea..... Which of the following is supportive of asthma A. *FEV1 Reversible with bronchodilators* B. C. D. E. 17. Injury to Axilla, patient can't extend his index and loss of sensation over dorsum of thumb and index. Nerve damaged A. Ulnar B. Median C. *Radial* D. Axillary E. Musculoskeletal 18. Patient with stroke. Weakness in left leg and foot. Artery involved A. MCA B. *ACA* C. PCA D. ICA E. 19. 2 years old child with history of recurrent fractures without trauma. Same history in other members of family. What is the inheritance of the disease A. AR B. *AD* C. X linked recessive D. 20. Virus transmitted by Blood transfusion A. Hep A B. *Hep B* C. Hep C D. Hep D E. Hep E 21. 20 years old female with recurrent respiratory infections. On investigations Lymphocytes normal and plasma cells absent/decreased A. *CVID* B. Agammaglobulinemia C. Thymus agensis D. E. 22. Patient with HTN, has increased GFR. What is the reason for increased GFR. A. *Increased glomerular hydrostatic pressure* B. Increased glomerular oncotic pressure C. Increased Bowman capsule hydrostatic pressure D. E. 23. A young patient presented with sore throat fever and goiter. On examination his throat was congested, fever was 102F and goiter was observed. Labs showed TSH down, T3, T4 normal. What drug will you prescribe? A. Methimazole B. PTU C. *Co amoxiclav* D. Propranolol E. 24. Which of the following drug has highest bioavailability when given orally? A. *Propranolol* B. C. D. E. 25. Glucose is absorbed in PCT through A. Facilitated diffusion B. Primary active transport C. Simple diffusion D. *Secondary active transport* E. 26. Patient presented with outward deviation of Right eye. Which of the following nerve is damaged? A. Left occulomotor B. *Right occulomotor* C. Left trochlear D. Right trochlear E. Right abducens 27. Mitral valve opens in which phase of cardiac cycle? A. Mid of Atrial systole B. Start of atrial systole C. Atrial diastole D. *End of isovolumetric relaxation* E. 28. True regarding epinephrine A. Act on Beta receptors only B. Doesn't act on Alpha receptors C. Causes vasodilation D. Increases TPR? E. 29. Which of the following has the highest pre potential? A. Atrioventricular node B. Ventricle C. *Sinoatrial node* D. Atria E. 30. Patient with right sided weakness and has upper motor neuron lesion of facial nerve. Where is the lesion? A. Pons B. Midbrain C. Medulla D. *Internal capsule* E. 31. Activation of parasympathetic system will cause? A. Ejaculation B. Mydriasis C. *Bronchoconstriction* D. Sweating E. 32. A patient with pan systolic murmur and ...... A. AR B. MS C. TR D. *MR* E. 33. Young Patient with 5 episodes of vomiting and no other symptoms. On investigation an air.... fistula between tail and GIT. Where is the fistula? A. Colon B. Descending colon C. Stomach? D. Duodenum E. Jejunum 34. A female was advised eye drops for eye infection. Two days later she complains of sour taste. The drops from eyes go first into? A. Nasopharynx B. Oropharynx C. Mouth D. *Nose* E. 35. Increase viscosity of blood causes decrease in A. Systolic BP B. Diastolic BP C. Pulse pressure D. Capillary something E. 36. A patient with multiple splinters from blast injury. Surgeon trying to remove the splinters, open the pericardium and move her fingers behind the apex till it reaches...... A. Costodiaphragmatic recess B. Costomediastinal recess C. *Oblique sinus* D. Coronary sulcus E. 37. Scenario of patient with some carcinoma. Doctor advised Methotrexate. Methotrexate inhibits? A. Folic acid B. *Dihydrofolate reductase* C. D. E. 38. A young boy collapsed while playing in school and died. On autopsy..... medium vessel A. Giant cells arteritis B. Takayasu C. *Kawasaki* D. E. 39. Which of the following has repeated sequence of trinucleotides? A. Down syndrome B. Turner C. Klinefelter D. *Fragile X* 40. A patient came with Bee sting. Doctor is looking for his kit with injectable epinephrine. What is the doctor trying to avoid? A. Local reaction B. *Systemic anaphylaxis* C. D. E. 41. Father Rh positive and mother negative. First delivery went uneventful. Mother didn't receive Rhogam. Second baby born after eighteen months with symptoms of hydrops.... Which type of hypersensitivity? A. Type 1 B. *Type 2* C. Type 3 D. Type 4 E. (Other names of hypersensitivity also mentioned in bracket) 42. A 10 years old girl with symptoms of headache relieving with paracetamol. On investigation tumour if pineal gland seen. Which is the most common tumor of pineal gland? A. Pineocytoma B. Pinoblastoma ? C. D. E. 43. A child with recurrent history of tonsillitis. Surgeon advised tonsillectomy. During surgery bleeding from right tonsillar artery. Right tonsillar artery is a branch of? A. Lingual B. *Facial* C. Ascending pharyngeal D. Descending palatine E. 44. A patient after RTA came to ER. No history of blood loss. O/E BP was 80/40, pulse was 60 something(low) and warm peripheries. Type of shock? A. Septic B. Hypovolemic C. Anaphylactic D. *Neurogenic* E. 45. A girl with different BP at upper and lower limb and a murmur. On investigation anomaly seen ? A. Patent truncus arteriosus B. Coarctation of aorta ? C. Patent foramen ovale D. E. 46. T cells are related to (somewhat aisi hi short stem thi) A. ANCA B. Vasculitis C. *Insulin dependent DM* D. Insulin independent DM E. 47. A young lady died suddenly. Only short history of fever and headache. On autopsy heart is enlarged (weight mentioned) and small lymphocytes in the myometrium. Infectious cause is? A. *Coxsackie B virus* B. C. D. E. 48. A lady with pain abdomen radiating to back. Labs showed raised amylase and lipase. On investigation a cyst with necrosis seen. Type of necrosis A. *Fat necrosis* B. Coagulative C. Fibrinoid D. Liquifective E. 49. A patient with history of dysphagia to fluids for 3 months. Also episodes of vomiting food contents and no GERD. On CXR air fluid levels seen behind heart. Diagnosis A. Ca esophagus B. *Achalasia* C. Mallory weis D. E. 50. A patient came with Hashimoto thyroiditis and Conns syndrome. Diagnosis? A. *Schmidt syndrome* B. MEN 2A C. MEN 2B D. APC E. 51. A patient with dysphagia and other symptoms..... Endoscopy showed patches and discoloration but no ulcers. Long scenario. In end asked ...Barrett's esophagus increased the risk of? A. *Adenocarcinoma* B. Signet ring adenocarcinoma C. Squamous cell carcinoma D. E. 52. Scenario of a patient with cough and hemoptysis. On investigation a tumour was seen in right lower lobe. Histology showed well differentiated with keratin.... (Something with keratin, not keratin pearls). Diagnosis A. Small cell lung Carcinoma B. Large cell lung Carcinoma C. *Squamous cell carcinoma* D. E. 53. Feathery necrosis in liver is seen in A. Hemochromatosis B. Copper deposition C. D. E. 54. Pacemaker cells of intestine A. Myenteric layer B. Muscular layer C. *Interstitial cells of Cajal* D. E. 55. A patient underwent splenectomy post RTA. 2 months later came with shock like symptoms. Culture showed clusters of gram positive bacteria, catalase negative.... A. Staphylococcus Aureus B. *Streptococcus pneumonae* C. Staphylococcus epidermidis D. E. 56. Which type of polyp has potential to become malignant? A. Serratus B. Hemartomatous C. Adenomatous ? D. Hyperplastic E. Tubular 57. A scenario of dysphagia and other symptoms. On endoscopy a mass seen with intact mucosa. Histology showed spindle cells and CD 117 positive. Diagnosis? A. *GIST tumour* B. Leiomyoma C. Leiomyosarcoma D. Adenocarcinoma E. Squamous cell carcinoma 58. Baby 6 months age. Passes stool soon after every feed. Most likely.... A. Rectoanal reflex B. Anorectal reflex C. *Gastrocolic reflex* D. Ileocolic reflex E. 59. A female with dysuria. On culture gram positive, coagulase negative organism.... (Many features written down) with swarming motility on blood agar A. E. Coli B. *Proteus mirabilis* C. D. E. 60. Two siblings who lives most of the time in home away from sunlight. Which of the following is most likely deficienct in them? A. 24 hydrocholecalciferol B. 1-25 dihydrocholecalciferol ? C. D. E. 70. Patient with Hypercalcaemia and squamous cell carcinoma of lung found. Which is responsible for the symptoms? A. Parathyroid hormone B. ACTH C. *Parathyroid hormone related peptide* D. E. 71. Chemotherapy advised for a cancer. Tumour size shrink by? A. Necrosis B. Phagocytosis C. *Apoptosis* D. E. 72. Generalized lymphadenopathy. Large B cell lymphoma found. Treatment of choice? A. Surgery alone B. Surgery followed by chemotherapy C. Surgery followed by radiotherapy D. Radiation alone E. Chemotherapy? 73. Patient with symptoms of UTI. Bladder is protected from the microbes because of A. B. C. D. E. 74. A 20 years old female presents with primary amenorrhea. On examination breast developed with sparse axillary hair and vagina present. On USG absent ovaries and uterus. Diagnosis A. CAH B. *Androgen insensitivity syndrome* C. D. E. 75. A patient of Breast carcinoma. On investigation mets seen in peritoneum, liver and ovaries. Route of spread? A. Lymphatic B. Seeding of tumour C. *Venous connections* D. E. 76. A young man with testicular tumour. After resection it was found to be non-seminomatous. Which of the following will be raised? A. ALP B. Acid phosphatase C. *Beta HCG* D. PSA E. 77. A boy with diarrhea was prescribed a drug that acts on 5-HT3 receptor. A. Loperamide B. Aldosterone (not Alosetrone) C. D. E. 78. Asian cholangio..... caused by A. Schistosoma hematobium B. *Clonorsis sinensis* C. D. E. 79. A female with history of RTA and lower limb injury. Can't walk. Posterior discloation of femur. Which nerve is likely damaged? A. Femoral B. Obturator C. *Sciatic* D. E. 80. A patient with long history of betel net use. Which of the following is a premalignant lesion predisposing to squamous cell carcinoma of mouth? A. Leukoplakia ? B. Erythroplakia C. Submuscal fibrosis D. Actinic keratosis E. 81. History of cough and hemoptysis. On X-ray a lesion seen in upper lobe of lung. Histology showed a lesion with megacells (or some word starting with mega) A. Small cell lung Carcinoma B. *Large cell lung Carcinoma* C. Squamous cell carcinoma D. Adenocarcinoma E. 82. A patient was brought to ER. He had no pulse or breathing. CPR was started and he was intubated. No IV line maintained. Which of the following drugs is ineffective through ETT? A. Naloxone B. Epinephrine C. *Diazepam* D. Lidocaine E. 83. A newborn was intubated and CPR was started within 1 minute of birth. What is his agar score? A. *0-2* B. 3-4 C. 5-6 D. 7-8 E. 84. A tennis player came with weakness in thumb movements. ...... Posterior/deep branch of radial nerve is trapped by which muscle? A. Anconeus B. *Supinator* C. Brachioradialis D. E. 85. Head nurse was teaching student nurses about IM injections. She stressed specifically on intragluteal injections to be administered in superolateral quadrant. This is to prevent injury to which nerve? A. Superior gluteal B. Inferior gluteal C. *Sciatic* D. Femoral E. 86. Long scenario of Von-Geirke, diagnosis given. Enzyme deficient? A. Muscle phosphorylase B. *Glucose-6-phosphate* C. Fructokinase D. E. 87. During Patellar Reflex, where would the doctor hit the hammer? A. *Patellar ligament* ? B. Anterolateral patellar ligament. C. Lateral patellar ligament. D. medial patellar ligament 88. A patient with perforated peptic ulcer. Contents spill into lesser sac and cause peritoneal irritation. This sharp pain is carried by? A. Splanchnic sympathetic B. Parasympathetic splanchnic C. *Lower intercostal* D. E. 89. 15 years age. Signs of pallor, weakness and fever......Translocation (t15:17) ..... Which of the following is WHO classification? A. Acute lymphocytic leukemia minimally differentiated B. Acute lymphocytic leukemia undifferentiated C. Acute promylocetic leukemia ? D. E. 90. Scenario of DKA like symptoms in a young boy.... Last me asked.... Low insulin will cause A. Increased lipogenesis B. *Ketone bodies formation* C. D. E. 91. Beta globulin are synthesized in? A. B cells B. Plasma cells C. T cells D. *Spleen* E. 92. A young boy with absence seizures. Ethosuximide was prescribed. What is it's MOA? A. Activates GABA type B receptors B. Enhance GABA receptors C. *T type Ca channels* D. E. 93. Many types of microbes cause infections in human. Which of the following may have either DNA, RNA but never both? A. Bacteria B. Fungi C. *Viruses* D. Parasites E. 94. A young boy came with history of bouts of vomiting. Now not passing urine. On investigation BUN raised more than Creatinine. Diagnosis? A. ATN B. Post renal azotemia C. *Prerenal azotemia* D. E. 95. A patient with MI died on 5th day. What will be seen on autopsy A. Lymphocytes B. *Macrophages* C. Lymphocytes D. E. 96. A patient of MI. The artery supplying apex of heart is blocked. Which artery supply apex? A. PDA B. LCX C. *LAD* D. Left marginal artery E. 97. Finding in polycythemia rubra vera other than increased Hb? A. *Decreased erythropoietin* B. C. D. E. 98. A lady with pallor and weakness. Hb low , MCV low,..... pencil cells with occasional target cells. Which investigation to confirm the diagnosis? A. Ferritin B. *Hb Electrophoresis* C. D. E. 99. A lady with pregnancy at 30th week had uterine contractions. She is concerned if her baby will be able to breath. What does the breathing in neonates depends upon? A. Number of type 1 pneumocytes B. Number of type 2 pneumocytes C. Size of lung D. *Quantity of Surfactant* E. 100. Melanin deposition causes which pigmentation? A. Flesher rings B. Kaiser Fleisher ring C. Haab's Stria D. *Krukenberg spindle* E. 101. A lady came with inability to breastfeed her baby. History of difficult labour at home by midwife with heavy bleeding. (Other hormone defects signs also mentioned).... Diagnosis? A. *Sheehan* B. C. D. E. 102. Which drug increases metabolism of other drugs? A. Cimetidine B. *Phenobarbitone* C. D. E. 103. Elderly patient after stroke. difficulty in phonation and word forming. Area involved? A. Inferior posterior prefrontal cortex B. Motor area C. (Another area of frontal) D. E. 104. A patient with congenital anomaly. TOF. Which will be seen in this patient? A. Aortic stenosis B. Overriding pulmonary outflow tract C. *Right ventricular hypertrophy* D. Interatrial defect E. 105. Patient with ankle sprain due to excessive inversion while playing. Ligament damaged? A. Deltoid B. *Anterior talofibular* C. Posterior talofibular D. Calcaneonavicular E. 106. A patient presented with patechiae. No previous history of bleeding or family history. Which is the most likely cause? A. Platelets 50000 B. *Platelets 20000* C. Hemophilia D. E. 107. A patient of CLD with edema and ascites. Mechanism of ascites formation? A. Decreased colloidal pressure B. *Because of portal vein tributaries* C. D. E. 108. Regarding free fatty acids in the blood A. Metabolically inert ? B. C. D. E. 109. Pruritic xanthomas. Raised cholesterol, Chylomicrons and TGs. Type of hyperlipidemia? A. *Type 1* B. Type 2a C. Type 3 D. Type 4 E. Type 2b 110. Which has highest cholesterol? A. VLDL B. Chylomicrons C. HDL D. *LDL* E. IDL 111. RBCs membrane contain a protein which helps it pass through the small capillaries without breaking. A. *Spectrin* B. Fibrillin C. D. E. 112. A woman came for hysterectomy. She is a known asthmatic. Which analgesia should be given post operatively? A. Ketorolac B. *Pethidine* C. D. E. 113. Amino acids that are strictly ketogenic A. *Leucine and lysine* B. Leucine and isoleucine C. D. E. 114. A known hypertensive on clonidine came with BP of 200/104 mm Hg. On history it was revealed that he ran out of his medicine. What should be advised A. Don't advise medicine and refer to psychologist B. *Restart clonidine and check BP 12-24 hrs later* C. Stop clonidine and shift to BB D. E. 115. CCK released by A. *I cells of intestine* B. C. D. E. 116. A girl came with primary amenorrhea. On USG bicornuate uterus. What abnormality led to this? A. *Failure of fusion of paramesonephric duct* B. C. D. E. 117. A long scenario of signs/symptoms of bronchioles . At end asked which cells will be effected A. *Columar* B. Clara cells C. Macrophages D. E. 118. Antigens move through intestinal wall through. A. *M cells* B. Antigen presenting dendritic cells C. D. E. 119. Patient with acid base disorder...... Na 144, K+ 4.5, Cl 105 and HCO3 17. Calculate anion gap (no option of 26.5 correct was 22 if we don't add K) A. 24 B. *22* C. 20 D. E. 120. What helps in effective communication between patient and doctor A. *Active listening* B. C. D. E. 121. Thyroid gland develop from a depression in pharyngeal floor. It travels down to the neck (long scenario)..... It is called A. Thyroglossal diverticulum? B. Thyroglossal duct C. D. E. 122. Part of DNA not encoding but causing mutation (some statement like this) A. Trinucleotides repeat B. Tandem repeats?