*PATHOLOGY EXAM EDGE POINTS* Complement System Functions • C3b: Opsonization (tags pathogens for destruction) • C3a, C4a, C5a: Anaphylaxis (trigger inflammatory responses) • C5a: Neutrophil chemotaxis (attracts neutrophils to infection site) • C5b-9 (MAC): Cytolysis (forms membrane attack complex to destroy pathogens) Regards Dr.Vishnupriya 💉