For the acute management of hemodynamically unstable pt with pulmonary embolism : Continue anticoagulation with UFH for several hours after the end of thrombolysis in before switching to apixaban or rivaroxaban; low molecular weight heparin (LMWH) is an alternative if these are unsuitable. UFH may be administered during continuous infusion of alteplase, but should be discontinued during infusion of streptokinase or urokinase​. 🏳️