Prewetting pipette tips before measuring liquids is a good laboratory practice to improve accuracy and precision. Here’s why: 1. *Minimizes Evaporation* – Prewetting conditions the tip with the liquid, reducing evaporation and ensuring a more consistent volume transfer. 2. *Improves Consistency*– It helps achieve uniform dispensing by coating the inner surface of the tip with the liquid, preventing liquid retention. 3. *Enhances Accuracy* – Ensures that the measured volume is closer to the intended value, especially for volatile or viscous liquids. *How to Prewet a Pipette Tip* Aspirate and dispense the liquid back into the original container 2–3 times before measuring the final volume. This technique is especially crucial when working with small volumes, organic solvents, or high-viscosity solutions. Honey T Scientific Ltd Honey T SciTech Fabrications.