Good evening! I am so sorry to hear about your wife's persistent leg pain, must have cost you so much.  Since the pain has lasted for 4 years and hasn’t completely responded to treatment, it’s important to find what  the exact cause is.  The reason is that different factors can cause leg pain. So, it could be nerve-related, joint-related, or even related to some changes from pregnancy and childbirth. My recommendation is that she see a specialist, like an orthopedic doctor or neurologist, for proper diagnosis.  However, for now, she can try gentle exercises, physical therapies that can help in pain management. I wish her  a speedy recovery🙏🏽❤️