Diagnosing & Treating PUPPP in Pregnancy 🔎 Case: A pregnant female in her third trimester presents with itchy papules and plaques on the abdomen. Notably, there is peri-umbilical sparing, which is a key diagnostic clue. 💡 Diagnosis: PUPPP (Pruritic Urticarial Papules and Plaques of Pregnancy) — a common pregnancy-related skin condition that typically occurs in the third trimester. 💊 Treatment: Safe antihistamines that can be given during pregnancy include: ✅ Polaramine (Dexchlorpheniramine) – Preferred for its safety in pregnancy. ✅ Cetirizine – Non-sedating option, generally safe in pregnancy. ✅ Loratadine – Another non-sedating antihistamine with a good safety profile. ⚠️ Why Treatment Is Important: Untreated PUPPP can significantly impact the mother’s quality of life due to intense itching. Using safe antihistamines helps control symptoms without harming the baby. 💡 Remember: Always choose medications with proven safety in pregnancy.