His Highness Prince Karim Al-Hussaini, Aga Khan IV, 49th hereditary Imam of the Shia Ismaili Muslims and descendant of the Prophet Muhammad (peace be upon him), passed away peacefully in Lisbon on 4 February 2025, aged 88, surrounded by his family. The announcement of his designated successor will follow. Building on foundations laid by his grandfather Sir Sultan Mahomed Shah, during his lifetime, Aga Khan IV grew the Aga Khan Health Services with the aim of improving the quality of life and healthcare for people in the developing world. In collaboration with other AKDN institutions, today we provide quality health care to 12 million people annually. The staff and volunteers of the Aga Khan Health Services offer our condolences to the family of His Highness and to the Ismaili community worldwide. As we honour the legacy of our founder, Prince Karim Aga Khan, we continue to work with our partners to improve the quality of life for individuals and communities across the world.