• Herpes Simplex Virus - Recurrent outbreaks (stays in the body for life) - Neonatal herpes in newborns (transmitted from the mother) - Herpes encephalitis (brain infection) - Anxiety and depression • Human Immunodeficiency Virus - Progression to AIDS Opportunistic infections like: - Tuberculosis - Toxoplasmosis - Candidiasis - Cytomegalovirus - Certain cancers - Memory loss - Heart and kidney disease - Wasting syndrome. These complications are serious and can lead to a severely unsatisfactory quality of life.