Urgent indication for Kidney Replacement Therapy (KRT)?? * Severe metabolic acidosis refractory to medical treatment * Pulmonary edema * Uremic complications (pericarditis, encephalopathy, bleeding) * Severe hyperkalemia refractory to medical treatment * Intractable fluid overload coupled with organ dysfunction * Concomitant intoxication with a dialysable drug or toxin Relative indication? * Progressive and/or persistent AKI (sCr >3× baseline and/or profound oliguria) * Severe nonkidney organ dysfunction worsened by AKI * Worsening trajectory of critical illness