
UPSC Science Technology UPSC UPSC UPSC UPSC Upsc Upsc Upsc Upsc UPSC BPSC MPPSC UPPSC CAPF CDS NDA™
June 13, 2025 at 06:49 AM
🦠 Using Bacteriophages to Combat AMR
📍 Background
✅ Antibiotics are losing effectiveness; 5 million die annually from AMR, may double by 2050.
✅ No major pharma investment in new antibiotics due to low financial incentives.
📍 Bacteriophages as Solution
✅ These are “good viruses” that kill bacteria; found in soil, water, gut.
✅ Can be used for burns, UTIs, respiratory infections etc.
📍 Strategies
✅ 1. Isolate bacteria, grow matching phage in lab, administer to patient.
✅ 2. Use pre-engineered phages to match bacteria types.
✅ Phage therapy is being revived, especially in Eastern Europe.
📍 Global Need
✅ No Western country has approved phage as drug yet, but emergency/special access routes exist.
✅ Magistral route in Belgium allows compounded phage medicines per patient.

❤️
1