A recent study found that 8.7% of patients with gastric cancer carried pathogenic variants in genes associated with cancer risk, including BRCA2, BARD1, MSH2, and MSH6. These findings highlight the importance of genetic testing in gastric cancer for improving patient management and potentially identifying hereditary syndromes. https://ascopubs.org/doi/10.1200/JCO.2025.43.16_suppl.e22602