
FIP Early Career Pharmaceutical Group
June 3, 2025 at 11:01 AM
🧠💊 KNOW YOUR MEDICINE: Atorvastatin
Atorvastatin is a statin that works by reducing cholesterol and triglyceride levels in your blood, which significantly lowers the risk of cardiovascular events🫀✨
✅ Mechanism of Action:
Atorvastatin inhibits HMG-CoA reductase, the rate-limiting enzyme in cholesterol biosynthesis. This decreases intrahepatic cholesterol and upregulates LDL receptors, leading to increased clearance of LDL-C from the blood.
📌 Result: Reduced LDL, total cholesterol, triglycerides, and increased HDL.
⚠ Adverse Effects:
* Myalgia (muscle pain)
* Elevated liver enzymes
* Rare: Rhabdomyolysis (muscular tissue breakdown), hepatotoxicity (liver damage).
❗ Important Points to note when taking Atorvastatin:
* Take at the same time daily (best taken at bedtime).
* Report unexplained muscle pain or weakness.
* Avoid excessive alcohol and grapefruit juice.
#knowyourmedicine #atorvastatin #pharmacyeducation #fip #statins #hearthealth #ldl #cholesterol #pharmacistsforhealth #think_health #think_pharmacy
References:
FDA. Atorvastatin calcium prescribing information.
DailyMed. Atorvastatin calcium – Label Information. U.S. National Library of Medicine.
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b687ba81-cb24-bbdf-5dd9-ab0e53dd480b
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