In the study titled “High Shear Stresses under Exercise Conditions Destroy Circulating Tumor Cells in a Microfluidic System” by Sagar Regmi, Afu Fu, and Kathy Qian Luo, published in *Nature Scientific Reports*, researchers investigated how varying levels of shear stress affect circulating tumor cells (CTCs). They used engineered human breast cancer cells with an apoptotic sensor to observe real-time cell death under different shear stress conditions (15, 30, 45, and 60 dynes/ cm’), simulating the forces experienced during exercise. The study found that at lower shear stress levels (15 and 30 dynes/cm-), many cells survived even after 18 hours. In contrast, higher shear stress levels (45 and 60 dynes/cm3) significantly reduced cell viability, with 60 dynes/cm being particularly effective, destroying almost all CTCs within 9 to 18 hours. The MTT assay confirmed that high shear stress conditions are much more effective at killing CTCs compared to lower levels, with substantial cell death occurring within just a few hours. This research underscores the potential of high shear stress, similar to that produced by intense exercise, as a powerful means of eliminating circulating cancer cells. On a related note, it’s important to acknowledge that exercise alone is not a panacea-cancer can still affect highly active individuals-it remains a valuable preventive measure for many. Embracing exercise as part of a comprehensive approach to cancer prevention can be both motivating and empowering for individuals seeking to bolster their overall health and well-being.