
INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH
May 25, 2025 at 02:31 AM
May 2025 FDA DRUG APPROVAL: Emrelis (telisotuzumab vedotin)
🫁 Mechanism of Action: Emrelis is a c-Met-directed antibody-drug conjugate (ADC) that targets cancer cells with high c-Met protein overexpression and delivers a cytotoxic payload to destroy them.
🫁 Indication: Approved for locally advanced or metastatic non-squamous non-small cell lung cancer (NSCLC) with high c-Met protein overexpression (≥50% tumor cells with strong staining).
🫁 Side Effects: Common adverse reactions include peripheral neuropathy, fatigue, decreased appetite, and peripheral edema.
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