What causes depression Depression is a complex condition with multiple potential causes. Here are some factors that can contribute to depression: Biological Factors 1. *Genetics*: Family history and genetic predisposition can play a role. 2. *Neurotransmitter imbalance*: Imbalances in serotonin, dopamine, and norepinephrine can affect mood. 3. *Hormonal changes*: Hormonal fluctuations, such as those experienced during pregnancy or menopause, can contribute to depression. Environmental Factors 1. *Trauma*: Experiencing traumatic events, such as abuse or loss, can increase the risk of depression. 2. *Stress*: Chronic stress, whether due to work, relationships, or other factors, can contribute to depression. 3. *Social isolation*: Lack of social support and feelings of loneliness can exacerbate depression. Psychological Factors 1. *Negative thinking patterns*: Pessimistic thought patterns and low self-esteem can contribute to depression. 2. *Mental health conditions*: Certain mental health conditions, such as anxiety or bipolar disorder, can increase the risk of depression. Other Factors 1. *Medical conditions*: Certain medical conditions, such as chronic pain or sleep disorders, can increase the risk of depression. 2. *Medications*: Some medications can have depression as a side effect. 3. *Substance abuse*: Substance abuse can contribute to depression. It's essential to note that depression is a complex condition, and each person's experience is unique. A mental health professional can help identify the underlying causes and develop an effective treatment plan.