โ›‘๏ธModรชrn Hรชalth-updatรชs๐Ÿ’Š๐Ÿ‡จ๐Ÿ‡ฆ๐Ÿ‡บ๐Ÿ‡ฒ e-Pharmacy
โ›‘๏ธModรชrn Hรชalth-updatรชs๐Ÿ’Š๐Ÿ‡จ๐Ÿ‡ฆ๐Ÿ‡บ๐Ÿ‡ฒ e-Pharmacy
February 7, 2025 at 07:37 PM
๐Ÿ’ก๐Ÿ’Š๐——๐—ผ๐—บ๐—ฝ๐—ฒ๐—ฟ๐—ถ๐—ฑ๐—ผ๐—ป๐—ฒ โ˜€๏ธworks by ๐—ฏ๐—น๐—ผ๐—ฐ๐—ธ๐—ถ๐—ป๐—ด ๐—ฑ๐—ผ๐—ฝ๐—ฎ๐—บ๐—ถ๐—ป๐—ฒ (๐——๐Ÿฎ) ๐—ฟ๐—ฒ๐—ฐ๐—ฒ๐—ฝ๐˜๐—ผ๐—ฟ๐˜€ in the chemoreceptor trigger zone (CTZ) and gastrointestinal tract. โ˜€๏ธunlike metoclopramide, domperidone ๐—ฑ๐—ผ๐—ฒ๐˜€ ๐—ป๐—ผ๐˜ ๐˜€๐—ถ๐—ด๐—ป๐—ถ๐—ณ๐—ถ๐—ฐ๐—ฎ๐—ป๐˜๐—น๐˜† ๐—ฐ๐—ฟ๐—ผ๐˜€๐˜€ ๐˜๐—ต๐—ฒ ๐—•๐—•๐—•, reducing the risk of extrapyramidal symptoms (EPS) such as dystonia and tardive dyskinesia. โ˜€๏ธ๐—ฟ๐—ฒ๐—ฐ๐—ผ๐—บ๐—บ๐—ฒ๐—ป๐—ฑ๐—ฒ๐—ฑ ๐—ฎ๐—ฑ๐˜‚๐—น๐˜ ๐—ฑ๐—ผ๐˜€๐—ฒ is 10 mg up to three times daily (maximum 30-40 mg per day), with treatment duration limited to the shortest possible time due to cardiac risks. โ˜€๏ธ๐—ฐ๐—ผ๐—บ๐—บ๐—ผ๐—ป๐—น๐˜† ๐˜‚๐˜€๐—ฒ๐—ฑ ๐˜๐—ผ relieve nausea and vomiting caused by delayed gastric emptying, chemotherapy, or Parkinsonโ€™s disease treatments. โ˜€๏ธ๐—ฐ๐—ฎ๐—ป ๐—ฝ๐—ฟ๐—ผ๐—น๐—ผ๐—ป๐—ด ๐˜๐—ต๐—ฒ ๐—ค๐—ง ๐—ถ๐—ป๐˜๐—ฒ๐—ฟ๐˜ƒ๐—ฎ๐—น, increasing the risk of torsades de pointes and sudden cardiac death, particularly at high doses or in patients with predisposing factors. โ˜€๏ธblocks dopamine (D2) receptors in the pituitary gland, leading to an ๐—ถ๐—ป๐—ฐ๐—ฟ๐—ฒ๐—ฎ๐˜€๐—ฒ ๐—ถ๐—ป ๐—ฝ๐—ฟ๐—ผ๐—น๐—ฎ๐—ฐ๐˜๐—ถ๐—ป ๐˜€๐—ฒ๐—ฐ๐—ฟ๐—ฒ๐˜๐—ถ๐—ผ๐—ป, which enhances breast milk production. โ˜€๏ธ๐—ป๐—ผ๐˜ ๐—ฒ๐—ณ๐—ณ๐—ฒ๐—ฐ๐˜๐—ถ๐˜ƒ๐—ฒ ๐—ณ๐—ผ๐—ฟ ๐—บ๐—ผ๐˜๐—ถ๐—ผ๐—ป ๐˜€๐—ถ๐—ฐ๐—ธ๐—ป๐—ฒ๐˜€๐˜€, as it does not act on histamine (H1) or muscarinic receptors, which are involved in vestibular balance.
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