
Atul’s Ophthalmology Pearls & OMO ( One Minute Ophthalmology)
February 6, 2025 at 05:20 AM
# HURON study
Chronic Uveitis evaluation of the Intravitreal Dexamethasone Implant
* Study Questions : efficacy and safety of the injectable dexamethasone intravitreal implant at 2 doses (0.35 mg and 0.70 mg) compared to placebo (sham)
* primary endpoint: vitreous haze grade 0
* Ozurdex group more likely than the sham group to have vitreous haze grade of 0 at 8 weeks
* <5% of eyes developed IOp ≥35 mm hg and <10% had IOp ≥25 mm hg.
* Cataracts developed in 15%
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