➡️The diagnosis is Desmoplastic small round cell tumor ( DSRCT) DSRCT Typically shows Desmin - nuclear dot like positivity and WT- 1 - nuclear positivity ✅WT1 & Desmin in DSRCT: Key Staining Patterns & Significance WT1 in DSRCT → Strong nuclear WT1+ due to EWSR1-WT1 fusion (t(11;22)), distinguishing it from Wilms tumor (N- terminal nuclear WT1+). ✅Desmin in DSRCT → Dot-like-nuclear Desmin+, unlike Rhabdomyosarcoma (strong, diffuse Desmin+). Significance → Nuclear WT1+ and perinuclear Desmin+ confirm DSRCT, helping differentiate it from Ewing Sarcoma (CD99+), Rhabdomyosarcoma (Myogenin+), and Lymphoma (CD45+). https://www.instagram.com/p/DGYCLYxyR__/?igsh=a3RsODU5ZTI3NmRw