HOW IS IT TREATED? Malaria is diagnosed through blood tests, which detects the parasite under a microscope or using Rapid Diagnostic Tests (RDTs). First line treatment depends on the type of malaria: - Uncomplicated malaria: Artemisinin-based Combination therapy (ACT) is the most effective treatment for P. Falciparum. - Severe malaria: Requires IV artesunate followed by oral ACT.