_*Concerns Over Bat-Borne Merbecoviruses*_ *Why in News:* Recent research highlights the potential risks of merbecoviruses, particularly the HKU5 subgroup, which may pose a threat to human health. *Key Points:* * Merbecoviruses, related to MERS-CoV, were largely overlooked until MERS in 2012. * HKU5 subgroup shows signs of potential human transmission, with mutations possibly allowing cross-species infection. * The virus uses spike proteins to bind to ACE2 receptors, similar to SARS-CoV-2. * HKU5 viruses have been detected across Asia, Europe, and Africa, with potential transmission to minks. * Wet, humid environments may aid virus maturation and spillover events.