
CSIR-CDRI Lucknow
May 28, 2025 at 06:04 AM
🚨 #justpublished in Journal of Medicinal Chemistry
A new study from CSIR-Central Drug Research Institute, Lucknow, India, led by Dr. Akhilesh K. Tamrakar and Dr. K.V. Sashidhara, reports the discovery of phthalazinone-triazole hybrids synthesized via Click chemistry.
The paper, with Ajay Kishor Kushawaha and Arvind Kumar Jaiswal as lead authors, highlights these compounds' ability to stimulate GLUT4 translocation in skeletal muscle, an important mechanism for glucose regulation. This work opens new avenues for the development of effective therapies to manage diabetes.
👏 Congratulations to all authors!!
Ajay Kishor Kushawaha, Arvind kumar Jaiswal, Pawan Kumar, Dr. Sarita Katiyar, Rahul Baghel, Hemlata Bhatt, Jay Gupta, Alisha Ansari, Poonam Yadav, Ishbal Ahmad, Abhijit Deb Choudhury, Rabi Sankar Bhatta, Akhilesh K. Tamrakar and Koneni V. Sashidhara
🔗 Read the full article: https://pubs.acs.org/doi/full/10.1021/acs.jmedchem.4c02615
#diabetesresearch #medicinalchemistry
