
7sevencontinents
June 1, 2025 at 02:14 PM
*400 Embryology Of The Nervous System*
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1. The nervous system begins to develop during
A. Week 2
B. Week 3
C. Week 4
D. Week 5
Answer: B
2. The first indication of nervous system development is the
A. Formation of the neural tube
B. Appearance of the neural crest
C. Formation of the notochord
D. Thickening of the ectoderm to form neural plate
Answer: D
3. The neural plate forms from the
A. Mesoderm
B. Ectoderm
C. Endoderm
D. Notochord
Answer: B
4. The notochord induces the overlying ectoderm to become
A. Neural crest
B. Neural groove
C. Neural plate
D. Somites
Answer: C
5. The neural plate begins to form at the
A. Cranial end
B. Caudal end
C. Midline
D. Lateral margin
Answer: A
6. The lateral edges of the neural plate elevate to form the
A. Neural crest
B. Neural folds
C. Neural tube
D. Neural groove
Answer: B
7. The depression formed between the neural folds is called the
A. Neural crest
B. Neural canal
C. Neural groove
D. Central canal
Answer: C
8. Fusion of the neural folds begins in the
A. Cranial region
B. Cervical region
C. Caudal region
D. Lumbar region
Answer: B
9. The neural tube forms by the
A. Regression of the primitive streak
B. Folding and fusion of the neural folds
C. Migration of mesoderm
D. Proliferation of neuroepithelium
Answer: B
10. The open ends of the neural tube are known as
A. Anterior and posterior grooves
B. Cranial and caudal fissures
C. Rostral and caudal neuropores
D. Brain and spinal cord openings
Answer: C
11. The neural tube closes first in the
A. Cervical region
B. Cranial region
C. Caudal region
D. Thoracic region
Answer: A
12. The rostral neuropore closes on day
A. 23
B. 25
C. 27
D. 28
Answer: B
13. Failure of rostral neuropore to close results in
A. Spina bifida
B. Hydrocephalus
C. Anencephaly
D. Encephalocele
Answer: C
14. The caudal neuropore closes on day
A. 23
B. 25
C. 27
D. 28
Answer: D
15. Failure of caudal neuropore to close causes
A. Encephalocele
B. Meningoencephalocele
C. Spina bifida
D. Anencephaly
Answer: C
16. Neural crest cells arise from
A. Lateral plate mesoderm
B. Ectoderm at the tip of neural folds
C. Endodermal thickening
D. Neural groove floor
Answer: B
17. Neural crest cells give rise to all of the following except
A. Dorsal root ganglia
B. Adrenal medulla
C. Melanocytes
D. Motor neurons
Answer: D
18. The spinal cord develops from the
A. Caudal neural crest
B. Ectoderm
C. Neural tube caudal to the fourth pair of somites
D. Midline mesoderm
Answer: C
19. The wall of the neural tube consists of
A. Pseudostratified columnar epithelium
B. Stratified squamous epithelium
C. Simple cuboidal epithelium
D. Ciliated columnar epithelium
Answer: A
20. Neuroepithelial cells differentiate into
A. Neuroblasts and glioblasts
B. Ganglion cells only
C. Astrocytes only
D. Ependymal cells only
Answer: A
21. Neuroblasts are precursor cells that give rise to
A. Astrocytes
B. Microglia
C. Neurons
D. Oligodendrocytes
Answer: C
22. The first cells to differentiate from neuroepithelial cells are
A. Glioblasts
B. Microglia
C. Ependymal cells
D. Neuroblasts
Answer: D
23. Neuroblasts lose their ability to divide and migrate to form the
A. Mantle layer
B. Marginal layer
C. Ependymal layer
D. Neural crest
Answer: A
24. The mantle layer eventually forms the
A. White matter
B. Grey matter
C. Choroid plexus
D. Ventricular system
Answer: B
25. The marginal layer of the neural tube forms the
A. White matter
B. Grey matter
C. Central canal
D. Choroid plexus
Answer: A
26. The mantle layer thickens to form two regions known as
A. Roof and floor plates
B. Basal and alar plates
C. Dorsal and ventral plates
D. Lateral and medial plates
Answer: B
27. The alar plate is primarily associated with
A. Motor function
B. Sensory function
C. Autonomic function
D. Cognitive function
Answer: B
28. The basal plate gives rise to
A. Sensory neurons
B. Autonomic neurons only
C. Motor neurons
D. Schwann cells
Answer: C
29. The dorsal part of the spinal cord is formed by the
A. Alar plate
B. Basal plate
C. Roof plate
D. Floor plate
Answer: A
30. The ventral part of the spinal cord is formed by the
A. Roof plate
B. Basal plate
C. Alar plate
D. Neural crest
Answer: B
31. The sulcus limitans separates
A. Left and right halves of the neural tube
B. Cranial and caudal ends
C. Alar and basal plates
D. Neural crest and neuroepithelium
Answer: C
32. Glioblasts differentiate into
A. Neurons
B. Astrocytes and oligodendrocytes
C. Microglia and neurons
D. Schwann cells
Answer: B
33. Microglia are derived from
A. Ectoderm
B. Mesoderm
C. Endoderm
D. Neural crest
Answer: B
34. The ependymal layer of the neural tube forms the
A. Choroid plexus
B. Lining of the central canal
C. Blood-brain barrier
D. Basal lamina
Answer: B
35. Spinal nerves are formed from
A. Basal and alar plates
B. Dorsal and ventral roots
C. Roof and floor plates
D. Central canal outgrowth
Answer: B
36. Ventral roots of spinal nerves originate from
A. Neural crest cells
B. Basal plate
C. Alar plate
D. Roof plate
Answer: B
37. Dorsal roots of spinal nerves arise from
A. Alar plate
B. Basal plate
C. Roof plate
D. Neural crest cells
Answer: D
38. The spinal cord initially occupies the entire length of the vertebral canal until
A. Week 4
B. Week 8
C. Month 3
D. Month 5
Answer: C
39. By birth, the spinal cord ends at the level of
A. L1-L2
B. T12
C. L4
D. L5
Answer: A
40. The filum terminale is derived from the
A. Neural crest
B. Terminal part of the spinal cord
C. Ependymal cells
D. Ventral horn
Answer: B