
زكاة العلم نشره 🌹
June 3, 2025 at 03:15 PM
Some notes regarding treatment of pseudomonal meningitis.
- initial therapy should include an antipseudomonal B-lactam (eg, ceftazidime, cefepime or meropenem 2 g IV every 8 hours) plus an aminoglycoside.
Imipenem-cilastatin is not recommended in meningitis because of the risk of seizures.
Aztronam or high dose ciprofloxacin 400 mg IV every 8 hours are alternatives.
In cases of multi drug resistant pathogens 🦠, continuous or extended infusion of B lactam may be considered to optimize target attainment.
Therapy should be continued for at least 21 days
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