Liver Enzyme Pattern Interpretation 1. AST and ALT greater than ALP → Hepatocellular Pattern This indicates damage to liver cells (hepatocytes). Common causes include: • Viral hepatitis (e.g., Hepatitis B, C) • Autoimmune hepatitis • Drug-induced liver injury (e.g., paracetamol overdose, anti-TB drugs) These conditions typically cause a significant rise in transaminases (ALT and AST), with ALT usually more elevated than AST in non-alcoholic causes.